For very strong negative (-) prescriptions, the edge thickness is the primary concern. For very strong positive (+) prescriptions, the center thickness is the concern. While high-index materials make a huge difference, the size and shape of the frame also play a role. Our use of aspheric design and minimum diameter surfacing are specifically designed to minimize this thickness, but a very strong prescription in a very large frame will always have more substance than a mild prescription in a small frame.